B25019 I By M. Faisal Hossain, BPharm, MPharm, PhD
Panax ginseng has been valued for centuries in Traditional Chinese and Korean medicine for its ability to boost energy, fight fatigue, and support overall wellness. Today, scientific research is exploring whether these traditional claims hold true. Here’s what modern studies say about ginseng’s effects on fatigue, energy, and mental performance.
What Makes Ginseng Special?
Active Compounds
The primary active ingredients in ginseng are ginsenosides—plant compounds known for their antioxidant, anti-inflammatory, and energy-supporting effects.
Where It Comes From
Panax ginseng is derived from the root of the ginseng plant, typically grown in Korea, China, and parts of Russia.
Traditional Use
Historically, ginseng was used to:
- Increase energy and vitality
- Reduce stress and enhance focus
- Strengthen overall body functions
What Does Modern Research Show?
1. Cancer-Related Fatigue
A 2023 review of seven studies found that ginseng significantly reduced fatigue and improved physical and emotional well-being in cancer patients. Luo WT, Huang TW. Cancer Nurs. 2023
2. Cognitive Performance and Mood
A 2025 clinical trial tested an energy shot containing Panax ginseng extract and other ingredients (a proprietary blend containing caffeine, taurine, vitamin B complex, and vitamin C) in healthy adults. Results showed improvements in mental speed, accuracy, mood, and reduced mental fatigue. O’Shea OK et al. Front. Nutr. 2025
3. Daily Fatigue in Healthy Adults
A 2024 Korean Red Ginseng study found that daily use for three weeks lowered fatigue levels compared to a placebo. It was safe and well tolerated. Lee Y-G et al. J Ginseng Res. 2024
4. Combination Supplements for Energy and Focus
A supplement containing ginseng, taurine, and vitamins improved energy, alertness, memory, and reduced inflammation after 12 weeks of use. Chhaya G et al. Med Res Arch. 2024
5. Exercise Performance and Recovery
A 2025 trial showed that wild ginseng extract enhanced muscle power, reaction time, and lowered stress hormones during intense exercise. Lee S et al. Int J Transl Med. 2025
How Does Ginseng Work?
- Supports cellular energy production
- Reduces oxidative stress and inflammation
- Helps balance stress hormones like cortisol
- Improves brain function and focus
Safety and Precautions
Ginseng is generally safe for short-term use, but mild side effects can occur:
- Insomnia
- Digestive upset
- Headache
Interactions: Ginseng may interact with blood thinners, diabetes medications, and certain other prescriptions. Pregnant or breastfeeding women and people with chronic health conditions should consult their healthcare provider before use.
Final Thoughts
Current evidence supports ginseng as a natural option for reducing fatigue, improving focus, and supporting recovery, either on its own or in combination with other nutrients. However, results can vary depending on product quality and dosage.
Tip: Choose ginseng from reputable brands and talk to a healthcare provider before starting any supplement.
References
- Luo WT, Huang TW. Cancer Nurs. 2023
- O’Shea OK et al. Front. Nutr. 2025
- Lee Y-G et al. J Ginseng Res. 2024
- Chhaya G et al. Med Res Arch. 2024
- Lee S et al. Int J Transl Med. 2025
Acknowledgment:
This blog was prepared with assistance from ChatGPT by OpenAI. The featured image was also created with the help of AI tools.
Note:
This content is for informational purposes only and is not intended as medical advice. Always consult your healthcare provider before starting any supplement.
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